Computational Bioengineering and Biophysics

The research seeks to develop and apply theoretical and computational methods across scales to fundamentally address physical, chemical, and biological phenomena and translate them into rational design and engineering of biological systems. Applications range from the development of advanced bio-based materials, biochemicals, and novel biocatalysts to disease prevention.

Topics include structure, dynamics, and rheology of soft matter (Khomami), antigen recognition by immune cells, intracellular transport, biochemical reaction networks (Abel), membrane and polymer biophysics, protein assemblies (Doxastakis, Abel), bioaffinty interaction analysis and simulation (Danquah), and metabolic network modeling, modular design of biological systems, and CRISPR-based genome editing (Trinh).